Your experiences with Amisulpride.

Steel Maiden · 22-09-2012, 06:43 PM

I am aware that Amisulpride is not marketed in the US and some other countries so my sample size will be reduced.

What are your experiences of Amisulpride, if you have taken it?

I am being very slowly titrated up on it while my Olanzapine might be decreased. My psychiatrist has an aim of 10mg Olanzapine + 600-800mg Amisulpride. Right now I am on 15mg Olanzapine + 300mg Amisulpride. It is working quite well, but improvement is still needed. (I used to be on 20mg Olanzapine but my mental health improved with the introduction of Amisulpride and the Olanzapine-induced sedation was worse than it is now).

whirlpools · 22-09-2012, 06:58 PM

I wasn't really on Amisulpride long enough to be able to tell... the time I did spend on it, it didn't really work very well for me and it made me quite constipated.

I hope it's successful for you.

Justsam · 23-09-2012, 10:59 AM

It was one of the better meds I had for my paranoia, but I still found I had quite a bit of anxiety. Soon after I started taking it, it caused my period to stop and I had started prouducing milk from my breasts.

Steel Maiden · 25-09-2012, 08:57 AM

Thanks. I'm actually hoping my periods stop, but lactation isn't nice; I had that on Risperidone.

My psych thinks increasing the Amisulpride will help with anxiety, but I have my doubts as Amisulpride is closer to a dopamine-2 blocker than a serotonin-dopamine antagonist.

Ami · 25-09-2012, 12:42 PM

I had this outragous akathesia and muscle pains, i would constantly jerk and severely shake and seize up 24hours a day (so no sleep for 5 days) ... worst 5 days ever. So I Dont know if it would have helped or not. x

Steel Maiden · 25-09-2012, 02:50 PM

That sounds awful.

I have a high tolerance for most meds, both in efficacy and side-effects. I tend to need doses at the higher end of the range for them to work and for side-effects to appear.

I've been on 25mg of Olanzapine (yes, 25mg - my psych increased it beyond the BNF range) before with minimal sedation/hunger.

However now that my illness is improving, and changing, I am managing on 15mg of Olanzapine, but the Amisulpride is in the process of being increased as some of my symptoms are still bothering me.