It always amazes me how so many of the greatest people who've lived have suffered from depression / mental illness, and how many amazing creations have come out of it. I think perhaps I'd make the distinction between anguish and depression, though. Orr maybe that's just me, but I find that when I'm at my absolute lowest there is no 'energy', there is no inspiration, there is nothing really. It's dull and monotonous and it prevents my stupid brain from working properly so that it's damn hard to even get by in school, never mind write anything expressive, that I actually like. It pretty much prevents me from doing anything useful.
I must say, I rather envy those people who find their depression a source of inspiration.
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