My partner has PCOS, underactive thyroid [once sufficiently medicated, this is not a barrier to losing weight or maintaining a healthy weight] and has been on olanzapine and other weight gaining anti-psychotics in the past. She lost weight from morbidy obesity to now a healthy BMI with Slimming world and is on the contraceptive pill to regulate periods/hormones. Her risk of diabetes is high too as it runs in her family at abnormally young ages, and because she is on quetiapine.
As far as I understand it the medication risk factor increase is a lot smaller than the weight risk factor. I believe there is a little bit of debate on the chicken or the egg relationship of weight and PCOS, some people feel PCOS is worsened by weight, and some people believe weight is gained because of PCOS, the reality is probably that both are in play.
Some people have very little problems with their PCOS, I don't know why that is, or what makes a bad case and a relatively unsymptomatic case but the symptoms associated with PCOS are only treated if they occur.
Losing weight is probably the best thing you can do for both diabetes risk and PCOS. It just means you need to eat healthily and be screened for diabetes regularly. Ask your GP how often he would like you to be tested, but I would guess at something like once a year given the medication you are on.
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