Your tastes seem pretty similar to mine (Big Bang Theory ftw), so I'll recommend a few things I like.
These have all been said but they bear repeating:
Buffy the Vampire Slayer (and spin-off
Angel, if you want, although in my opinion it's not as good),
Firefly (which is kind of a space western, quite funny but also dramatic),
Supernatural (good for the humour and action and, you know, cute main characters),
Once Upon a Time (kind of cheesy, in my opinion, but easy to watch and quite enjoyable),
Bones (crime show with some humour and romance and such),
How I Met Your Mother (hilarious show, first few seasons in particular),
Being Human (I've only seen a bit of the most recent remake, but I liked it well enough),
Teen Wolf (nowhere near as lame as it sounds).
I don't think these ones have been said, but they're worth a go:
Scrubs (kind of ridiculous comedy),
Community (seriously, watch it, you won't regret it),
Dollhouse (a little dark, a bit funny, and kind of thought-provoking),
Homeland (haven't seen it but my friends who like Game of Thrones and Lost also love this show).
Hit me up sometime and we can talk TV shows. I always have plenty of recommendations.
