By the sounds of it, u've tried alot of the modern anti-depressant meds. Maybe you can talk to your psych and ur psych might explore the older anti-depressant meds (tricyclics) and or even mood stabilisers if necessary. But the combination of psychotherapy and meds does work better than just having one or the other separately.
I guess the final alternative is ECT, but like i said, last option if nothing works at all and uve tried all options available. Hope that helps a bit.
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