I think you hit the nail on the head mentioning the guilt...that can definitely prevent you from disclosing your self-harm to your sister...and maybe you are worried about how she may react...
If you decide to talk to her about your self-harm, you could mention how difficult it is for you to talk about it due to the guilt. Also, you could mention what you need from her in order to be able to be honest about self harming (remember that you can ask, but she may not necessarily give you what you need).
These are just suggestions, I don't know what's going on in your family and the relationship with your sister, so it's up to you what you want to do...I know being honest is tough!
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