Sorry, I should have been clear. When I referred to chemicals I was speaking of the specific hormones you mentioned. The tablets I take affect my brains response to those hormones. When they are out of whack and causing a physiological depression, they are effective. When I am lost in bad memories and feeling sad, they do not, because no amount of hormone manipulation will get rid of the memories I have.
ETA, I take Sertraline, an SSRI.
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